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Magnesium Bisglycinate

Ingredient common name

Magnesium Bisglycinate

Muscle and tendon support*
Bone support*
Heart and blood vessel support*
Respiratory support*
Metabolic support*
Promotes women’s health* 

Patented ingredient name
TRAACS® Magnesium bisglycinate chelate

Manufacturer
Albion Laboratories, Inc.

Grown in
United States

Dietary sources
Spinach, Swiss chard, dark chocolate, pumpkin seeds, almonds, black beans, and avocados.
Magnesium bisglycinate has superior absorption. A 4-arm, crossover study found that serum levels of magnesium over an 8-hour period were the highest for magnesium bisglycinate, followed in order by dimagnesium malate, buffered magnesium bisglycinate, and magnesium oxide.

Glycine, the amino acid in magnesium bisglycinate, helps decrease the pH of the small intestine, which improves magnesium bisglycinate’s solubility and absorbability.*

Two separate glycine molecules occupy an active site on each magnesium molecule, which reduces magnesium’s propensity to complex with phytates and other substances that can inhibit absorption.

Magnesium bisglycinate has a lesser laxative effect. Because glycine takes up active binding sites on the magnesium molecule, less water can attach to the magnesium, which reduces the laxative effect typically seen in magnesium compounds.
  • Identification (via HPTLC)
  • Heavy metals
  • Microbes

Contained In

Clinical References

Support for metabolic syndrome

He K, Liu K, Daviglus M, et al. Magnesium intake and incidence of metabolic syndrome among young adults. Circulation 2006;113:1675-1682.

Fang X, Han H, Li M, et al. Dose-response relationship between dietary intake of magnesium . . . : a systematic review and meta-regression analysis of prospective cohort studies. Nutrients 2016;8(11). pii: E739.

Cardiovascular support

Kolte D, Vijayaraghavan K, Khera S, et al. Role of magnesium in cardiovascular diseases. Cardiol Rev 2014;22(4):182-192.

Cunha A, D'El-Rei J, Medeiros F, et al. Oral magnesium supplementation improves endothelial function . . . . J Hypertens 2017;35(1):89-97.

Kunutsor S, Khan H, Laukkanen J. Serum magnesium . . . in men: The Kuopio Heart Disease Study. Eur J Epidemiol 2016;31(10):1035-1043.

Women’s health

Enaruna N, Ande A, Okpere E. Clinical significance of low serum magnesium in pregnant women attending the University of Benin Teaching Hospital. Niger J Clin Pract 2013;16(4):448-453.

Bullarbo M, Ödman N, Nestler A, et al. Magnesium supplementation . . . in pregnancy: a randomized placebo-control trial. Arch Gynecol Obstet 2013;288(6):1269-1274.

Bone and muscle support

Farsinejad-Marj M, Saneei P, Esmaillzadeh A. Dietary magnesium intake, bone mineral density and risk of fracture: a systematic review and meta-analysis. Osteoporos Int 2016;27(4):1389-1399.

Welch A, Kelaiditi E, Jennings A, et al. Dietary magnesium is positively associated with skeletal muscle power and indices of muscle mass and may attenuate the association between circulating C-reactive protein and muscle mass in women. J Bone Miner Res 2016;31(2):317-325.

Sports performance

Setaro L, Santos-Silva P, Nakano E, et al. Magnesium status and the physical performance of volleyball players: effects of magnesium supplementation. J Sport Sci 2014;32(5):438-445.