What is Nicotinamide Riboside?

Nicotinamide riboside, or NR, is a naturally-occurring version of vitamin B3 that works within our cells to support a number of cellular processes that support healthy aging, cellular energy, brain function, liver health, and metabolism.*

1.  Supports cellular energy production*

The primary cellular targets of NR are NAD and the Sirtuins (sounds like a great name for a rock band, yes?). NAD stands for nicotinamide adenine dinucleotide. NAD is important in the conversion of food into cellular fuel. Food must be digested down to its smallest metabolic components – sugars, fats, and amino acids. 

These metabolic components are then used by the mitochondria in our cells to make ATP – cellular fuel. When this process works efficiently we have plenty of energy because we have lots of mitochondria in our cells making a lot of ATP. However, this process slows down as we age and as other environmental and cellular insults adversely affect our bodies.

We can mitigate this situation with substances that promote the activity of a specific group of enzymes called sirtuins, because the sirtuin enzymes help our cells be more metabolically efficient – IF we are making enough NAD.

2.  Supports brain function*

Increasing NAD and sirtuins in brain cells and nerves stimulates enzymes that support cognitive function and neuroplasticity – the ability of our brain cells to learn and adapt to their environment.* This also increases the activity of another enzyme called PCG-1-alpha, which stimulates our cells to create more mitochondria within them, which, of course, creates more energy.*

3.  Supports healthy metabolic function*

When NAD and the sirtuins are supported, our cells are more metabolically active and more efficient at converting food to fuel. This can help us more effectively use insulin, cholesterol, and have a normal inflammatory response.*

4.  Supports normal liver function*

One of the most metabolically active types of cells in the body are liver cells. Liver cells are constantly metabolizing the substances we make in our bodies, like hormones and neurotransmitters, as well as detoxifying substances from within (called endotoxins) and from without (exotoxins, from food and the environment). When we support NAD production and mitochondrial function we support these essential cells and reduce the potential for fat to deposit in the liver.* We also promote a normal inflammatory response.*

5.  Promotes healthy aging*

Supporting NAD production and the sirtuin enzymes has been shown in animal studies to slow the usual ravages of aging. While nothing can really work as an “anti-aging” supplement, helping sirtuins, NAD, and mitochondria can help support healthy aging.*

Contrary to wild sales pitches, no single nutritional supplement is a magic bullet. However, NR promotes optimal metabolic function and cellular energy production, mitochondrial activity, and a normal inflammatory response.* These cellular functions can help us age well, exercise better, maintain normal metabolism and detoxification, and help us stay clear-headed.*

Learn more about NiaCel® and NiaCel-250®

NiaCel and NiaCel-250 support energy, cognitive function, and healthy aging.* Niacel (Nicotinamide Riboside) increases mitochondrial biogenesis and NAD+ levels, which decline as we age.* It also provides neurological, metabolic, and muscle endurance support.*