Although biological age is certainly not a new term, it is also just as certainly the hottest topic in health care as the generation of boomers enters their golden years.

Biological age helps explain why some individuals of the same age have profound differences in capabilities – why some run marathons and scale mountains, while others are riddled with health conditions and require around-the-clock care. Biological age is not chronological age, which is your age based on when you were born. Rather, biological age is how old your body behaves physiologically. 

Normal environmental damage, dietary habits, lack of proper exercise, untreated physical or mental health issues, and even social stimulation can all affect the “age” of your cells. Your biological age is altered by how much “damage” your body accumulates over time. Although your body might not feel old in your 30s or 40s, simple everyday behaviors can be affecting you internally in ways that will alter your healthspan as you age.

Introducing Agebio

Thorne's sister company Onegevity is releasing its second product since the launch of Gutbio in January 2019. Agebio is the newest biological age test on the market and only requires a simple blood test.

Agebio uses blood biomarkers and a research-validated algorithm that uses hundreds of thousands of biomarkers to provide invaluable scores that estimate a person's biological, liver, kidney, lipid, metabolic, and heme/immune ages.

As you age, your risk for almost every prevalent disease increases.1 The research indicates that biological age is actually a better predictor of disease risk than is chronological age. Biological age is also highly associated with all-cause mortality and risk for numerous health conditions like diabetes, cancers, dementia, and organ-specific damage.2

Therefore, reversing or slowing your biological age clock can have a clinically meaningful impact on your health and longevity. Agebio was designed to help you do that. 

How does Agebio work?

Agebio version 1 allows you to upload your biomarker data into your private Onegevity portal, after which you receive all age-score insights immediately. It's simple – create a profile and use your biomarker data from a doctor's visit, a yearly physical exam, or bloodwork over the previous six months.

Your values are analyzed in a database that contains hundreds of thousands of other's biomarkers to estimate what your body looks like internally.

Your Agebio report will provide insightful biological age and rate of aging for your entire body and specific organs – so you will know if your liver is aging faster than your kidneys, or how old your immune system is compared to others. Your personalized recommendations are focused on the oldest age score and will provide resources on how to slow or reverse your age clock.

By changing one biomarker, you ultimately effect the rate at which your entire body is aging. 

Agebio version 2 will launch in Fall 2020. At that time you will have the option to purchase the Agebio blood panel through Onegevity, take the labwork requisition form directly to a Quest Diagnostics lab, and have your blood drawn without needing to see your doctor. Your bloodwork results, age scores, recommendations, and educational information will populate into your Onegevity profile in several days. 

What makes Onegevity's Agebio unique?

Agebio boasts an enormous database of diverse and longitudinal biomarkers that train the research-backed algorithm (Klemera-Doubal)3 to compute biological age scores. Because it has been tested to show unbiased accuracy across users and generations, the biological age predictions are not skewed – as some tests are – if you are analyzing chronologically younger or older adults.4

Housed on Onegevity's health intelligence platform, this proprietary algorithm uses machine learning and artificial intelligence to continuously refine its computation, scores, and recommendations. Therefore, you can take the Agebio test with the confidence that your age scores are valid, reliable, and sensitive to the slightest changes you might not even notice as you age.

And since Agebio uses blood biomarkers, results come back quickly – and its affordable and convenient for anyone looking to understand their state of health and wellness. 

Agebio version 1 is accessible to all adults, across the continuum of generations, in every state. For these reasons, Agebio is unlike any other biological age test on the market. 

Agebio Backstory

Agebio’s biological age evaluation was co-created by the science team at Onegevity Health and world-renowned aging researchers Leroy Hood, MD, PhD, and Nathan Price, PhD, through a joint venture, Aevum Aging. Dr. Hood is the inventor of groundbreaking scientific instruments, including DNA and protein sequencers, that significantly advanced treatment opportunities for HIV treatments and the Human Genome Project.

He is one of 15 scientists to be elected into all three national academies – the National Academy of Sciences, the National Academy of Engineering, and the National Academy of Medicine. He has received 17 honorary degrees and the distinguished National Medal of Science from President Obama in 2013.

Dr. Price co-directs the Hood-Price Integrated Lab for Systems Biomedicine at the Institute of Systems Biology in Seattle. Both individuals have been selected for numerous prestigious awards for their work in pioneering “scientific wellness,” and between the two of them they have more than one thousand publications in this field. Read more about this joint venture announcement here

Thorne is proud to support Onegevity Health and Aevum Aging in advancing science in the aging field. We encourage you to check out Agebio and discover how your nutrition, supplementation, and lifestyle has impacted you over the years and can transform the way you age in the future!  


References

  1. Niccoli T, Partridge L. Aging as a risk factor for disease. Curr Biol 2012;22(17):R741-R752.
  2. Levine M. Modeling the rate of senescence: can estimated biological age predict mortality more accurately than chronological age? J Gerontol A Biol Sci Med Sci 2013;68(6):667-674. 
  3. Klemera P, Doubal S. A new approach to the concept and computation of biological age. Mech Ageing Dev 2006;127(3):240-248.
  4. Jia L, Zhang W, Chen X. Common methods of biological age estimation. Clin Interv Aging 2017;12:759-772.