Indole 3-Carbinol
Indole 3-Carbinol Details
The 2-hydroxy estrogens, less active than the 16-hydroxy estrogens, generally are eliminated more rapidly from the body. One prospective study found postmenopausal women with the most favorable urinary 2:16-hydroxyestrone ratio were most likely to maintain good female health. Preliminary studies have examined the efficacy, safety, and optimal supplementation of Indole-3-Carbinol (I3C). A 12-week phase 1 trial conducted on 17 women found a 66-percent increase in urinary 2:16-hydroxyestrone ratio with administration of 400 mg I3C daily.
The 2-hydroxy estrogens, less active than the 16-hydroxy estrogens, generally are eliminated more rapidly from the body. One prospective study found postmenopausal women with the most favorable urinary 2:16-hydroxyestrone ratio were most likely to maintain good female health. Preliminary studies have examined the efficacy, safety, and optimal supplementation of Indole-3-Carbinol (I3C). A 12-week phase 1 trial conducted on 17 women found a 66-percent increase in urinary 2:16-hydroxyestrone ratio with administration of 400 mg I3C daily.
Warnings
Risk Information:
Consult a health-care practitioner if you develop a skin rash. Consult a health-care practitioner prior to use if you are attempting to conceive; if you are taking antacids, H2 blockers, or proton-pump inhibitors; or if you have a liver disorder or develop liver-related symptoms (e.g., abdominal pain, jaundice); or if you have low estrogen or symptoms of low estrogen. Consult a health-care practitioner prior to use If you are taking any medications. Do not use if you are pregnant or breastfeeding.
Do not use if security seal inside cap is broken. Store tightly sealed in a cool dry place.
Risk Information:
Consult a health-care practitioner if you develop a skin rash. Consult a health-care practitioner prior to use if you are attempting to conceive; if you are taking antacids, H2 blockers, or proton-pump inhibitors; or if you have a liver disorder or develop liver-related symptoms (e.g., abdominal pain, jaundice); or if you have low estrogen or symptoms of low estrogen. Consult a health-care practitioner prior to use If you are taking any medications. Do not use if you are pregnant or breastfeeding.
Do not use if security seal inside cap is broken. Store tightly sealed in a cool dry place.
How to Use
Recommended Use or Purpose (Adults):
Helps support healthy estrogen metabolism and a healthy estrogen metabolite ratio. Source of antioxidants for the maintenance of good health.
Recommended Dose (Adults):
Take 1 capsule one to two times daily, or as recommended by your health professional.