Enhances sleep and helps manage stress*
5-HTP increases serotonin levels to promote restful sleep, manage stress, and decrease sugar cravings.* It contains pyridoxal 5'-phosphate, the active form of vitamin B6 and the necessary cofactor for the conversion of 5-HTP to serotonin.
5-Hydroxytryptophan (5-HTP) is the intermediate metabolite the body produces when it initiates the process of converting the essential amino acid L-tryptophan to serotonin. Therefore, supplementation with 5-HTP will bypass the conversion of L-tryptophan into 5-HTP by the enzyme tryptophan hydroxylase – which is the rate-limiting step in the synthesis of serotonin – and is a conversion that can be inhibited by a number of factors, including stress, insulin resistance, increasing age, and deficiencies of vitamin C, folate, and iron.* 5-HTP is well absorbed when taken orally, with about 70 percent going into the bloodstream.* Intestinal absorption of 5-HTP does not require the presence of a transport molecule, and its absorption is not affected by the presence of other amino acids; therefore, 5-HTP can be taken with meals without reducing its effectiveness. 5-HTP has been shown to have a beneficial impact on mood, sleep, carbohydrate cravings, and discomfort associated with fatigue.* Numerous studies of individuals with negative mood status have shown significant positive response with 50-300 mg of 5-HTP daily.*
To further facilitate serotonin production, Thorne's 5-HTP formula contains pyridoxal 5'-phosphate, the active form of vitamin B6 and the necessary cofactor for the conversion of 5-HTP to serotonin. 5-HTP is commercially produced by extraction from the seeds of the African plant, Griffonia simplicifolia.
Servings per container: 45
Vitamin B6 (as Pyridoxal 5'-Phosphate) 6.8 mg.
5-Hydroxytryptophan 100 mg.
Other Ingredients: Microcrystalline Cellulose, Hypromellose (derived from cellulose) capsule, Leucine, Silicon Dioxide.
This product is contraindicated in an individual with a history of hypersensitivity to any of its ingredients.
If pregnant, nursing, or trying to conceive, consult your health professional before using this product.
5-Hydroxytryptophan should be used with caution in an individual currently being treated with an SSRI, MAO inhibitor, or other antidepressant medication.
Bringing health to your home.
Our new suite of Thorne tests allow you to take steps towards a healthier lifetsyle while in the comfort of your own home. No lab visit required. Ever. Learn more about Thorne home tests and find out which test is right for supporting you in becoming your best self.
People Like You Also Viewed
Supports healthy bones and muscles, cardiovascular function, and immune function*
Promotes lean muscle mass and strength, and enhances energy production*
Contains natural-source GABA, a brain chemical to promote a calm state of mind and restful sleep*