New look. Same formulas. Reintroducing you to Thorne. Details
Free shipping. Get free shipping on all orders. Details
 

New look. Same formulas.

You probably noticed our new website, new logo, and new product labels. While our looks may have changed, our commitment to science and quality products remains untouched. Every product is still manufactured with the highest quality and safety standards in the world and still contains the exact same formula as before.

Please note that during the transition you might receive products with the former label as well as the new label. In every case, however, all of our products, regardless of label, are shipped with the maximum shelf-life in mind.

Learn more about our brand evolution.

 

Free shipping

Get free ground shipping on all retail orders and on wholesale orders valued at $99 and up.

(Contiguous United States only).

5-Hydroxytryptophan

SKU SA503

Enhances sleep and helps manage stress*

5-HTP increases serotonin levels to promote restful sleep, manage stress, and decrease sugar cravings.* It contains pyridoxal 5'-phosphate, the active form of vitamin B6 and the necessary cofactor for the conversion of 5-HTP to serotonin.

$29.90
Benefits
Mood, Sleep
The serotonin levels in the body are associated with the regulation of sleep, mood, and appetite. A balanced serotonin level has been shown to support restful sleep, good mood, and decreased sugar cravings.* There are several ways to support a healthy serotonin level. L-tryptophan and 5-Hydroxytryptophan (5-HTP) are both precursors to serotonin. However, supplementation with 5-HTP is preferable, because unlike L-tryptophan, 5-HTP cannot be shunted into other uses in the body, such as niacin or protein production. 5-HTP is well absorbed by the body and easily crosses the blood-brain barrier where it can increase the synthesis of serotonin in the central nervous system.* And 5-HTP can be taken with meals without reducing its effectiveness.*

5-Hydroxytryptophan (5-HTP) is the intermediate metabolite the body produces when it initiates the process of converting the essential amino acid L-tryptophan to serotonin. Therefore, supplementation with 5-HTP will bypass the conversion of L-tryptophan into 5-HTP by the enzyme tryptophan hydroxylase – which is the rate-limiting step in the synthesis of serotonin – and is a conversion that can be inhibited by a number of factors, including stress, insulin resistance, increasing age, and deficiencies of vitamin C, folate, and iron.* 5-HTP is well absorbed when taken orally, with about 70 percent going into the bloodstream.* Intestinal absorption of 5-HTP does not require the presence of a transport molecule, and its absorption is not affected by the presence of other amino acids; therefore, 5-HTP can be taken with meals without reducing its effectiveness. 5-HTP has been shown to have a beneficial impact on mood, sleep, carbohydrate cravings, and discomfort associated with fatigue.* Numerous studies of individuals with negative mood status have shown significant positive response with 50-300 mg of 5-HTP daily.*

To further facilitate serotonin production, Thorne's 5-HTP formula contains pyridoxal 5'-phosphate, the active form of vitamin B6 and the necessary cofactor for the conversion of 5-HTP to serotonin. 5-HTP is commercially produced by extraction from the seeds of the African plant, Griffonia simplicifolia.
Take 1-2 capsules three times daily or as recommended by your health professional.

Servings per container: 45
Two Capsules Contain:
Vitamin B6 (as Pyridoxal 5'-Phosphate) 6.8 mg.
5-Hydroxytryptophan 100 mg.

Other Ingredients: Microcrystalline Cellulose, Hypromellose (derived from cellulose) capsule, Leucine, Silicon Dioxide.
ALLERGY WARNING S
This product is contraindicated in an individual with a history of hypersensitivity to any of its ingredients.


PREGNANCY WARNING
If pregnant, nursing, or trying to conceive, consult your health professional before using this product.


INTERACTIONS/CONTRAINDICATIONS
5-Hydroxytryptophan should be used with caution in an individual currently being treated with an SSRI, MAO inhibitor, or other antidepressant medication.

Bringing health to your home.

Our new suite of Thorne tests allow you to take steps towards a healthier lifetsyle while in the comfort of your own home. No lab visit required. Ever. Learn more about Thorne home tests and find out which test is right for supporting you in becoming your best self.

People Like You Also Viewed

Vitamin D-5,000

Supports healthy bones and muscles, cardiovascular function, and immune function*

Amino Complex - Berry

Promotes lean muscle mass and strength, and enhances energy production*

PharmaGABA-250

Contains natural-source GABA, a brain chemical to promote a calm state of mind and restful sleep*

Related Health Concerns