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According to the American Veterinary Medical Association, one in 10 dogs suffers from poor cardiovascular health. Although some dogs have a genetic predisposition to cardiovascular problems, other factors such as nutritional deficiencies and obesity can certainly contribute.

A number of dietary supplements, including coenzyme Q10 (CoQ10), vitamin E, L-carnitine, taurine, potassium, and magnesium have generated positive research results in helping to maintain a healthy heart. In addition, various botanical substances can provide cardiac support.

Bio-Cardio for small animals combines the antioxidant and cardio-protective qualities of CoQ10 with other cardio-protective nutrients and botanicals. Research on CoQ10 in animals demonstrates it promotes the heart's oxygen utilization and helps maintain a healthy myocardium.

Certain amino acids are essential to cardiac function. Supplementation of taurine for supporting healthy cardiac function in cats has been well established, because unlike humans and dogs, cats do not make taurine. Thus, in the feline population, taurine is considered an essential amino acid. L-carnitine is essential for cellular energy production in the mitochondria and supports muscle metabolism, including the heart muscle. Supplementation has been shown to improve appetite and exercise tolerance in dogs. Dimethylglycine enhances oxygen usage and improves muscle metabolism.

Vitamin E provides essential antioxidant activity in fat-soluble tissues; selenium is a necessary cofactor for glutathione peroxidase. Maintaining a healthy level of antioxidants to balance oxidative stress is essential for all tissues of the body, including the heart.

Magnesium and potassium are essential minerals for healthy cardiac contractility and maintaining already normal heart rhythm; magnesium is essential for regulating vascular smooth muscle tone. Deficiencies of these two minerals often occur concurrently; therefore, it is essential to replete both of them.

Botanicals in Bio-Cardio include Crataegus, Tribulus, and Terminalia, which contribute to healthy heart muscle function, and Eleutherococcus, an adaptogen, which promotes physical stamina.