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Bio-B12®

Out of Stock-
Orders still accepted and will ship when available.


vitamin B12 and folic acid in a base of papain to enhance absorption*

  • a unique Thorne product
  • a viable option to sublingual B12 products
  • without preservatives, magnesium stearate, or other lubricants and diluents
  • made without flowing agents that can inhibit bioavailability

Item Product Size Price
B120 Bio-B12®
Out of Stock
60 Vegetarian Capsules $16.25

Product Information

In order for vitamin B12 to be absorbed in the gastrointestinal tract, it first needs to be bound in the stomach to a protein called R-protein. In the intestines pancreatic proteases cause the R-protein to release vitamin B12 to bind with intrinsic factor, making it absorbable. Thorne's Bio-B12 contains methylcobalamin (an active form of vitamin B12) and folic acid in a base of papain. Papain is a potent protein-digesting enzyme from papaya that also results in the release of vitamin B12 from the R-protein, thus facilitating the absorption process.* Zinc picolinate is included for support of the pancreas, which produces other digestive enzymes that facilitate the absorption process.*

Methylcobalamin (an active form of vitamin B12) is essential for recycling homocysteine and the formation of methyl donors involved in cardiovascular function, sleep, blood cell formation, and nerve function.* Most vitamin B12 supplements contain cyanocobalamin; however, the liver must first "detoxify" the cyanide molecule and attach a methyl group to form methylcobalamin from the cyanocobalamin. Methylcobalamin is already in the biologically active, tissue-ready form.* Evidence indicates the body utilizes methylcobalamin more efficiently than it does cyanocobalamin.* Research shows the quantity of cobalamin detected following a small oral dose of methylcobalamin is similar to the amount following administration of cyanocobalamin; but significantly more cobalamin accumulates in liver tissue following administration of methylcobalamin. Human urinary excretion of methylcobalamin is about one-third that of a similar dose of cyanocobalamin, indicating substantially greater tissue retention.*


Ingredients

One Capsule Contains:
Vitamin B12 (as Methylcobalamin) 1 mg.
Folic Acid 800 mcg.
Zinc (as Zinc Picolinate) 15 mg.
Papain* 75 mg.

Other Ingredients: Hypromellose (derived from cellulose) capsule, Microcrystalline Cellulose, Silicon Dioxide.

*An enzyme derived from Papaya (Carica papaya).

Suggested Use: Take 1 capsule one to three times daily or as recommended by a health-care practitioner.
Please read the warnings for this product on the warnings tab.

Statements and Warnings

ALLERGY WARNING
This product is contraindicated in an individual with a history of hypersensitivity to any of its ingredients.

Bio-B12 contains an ingredient derived from papaya.

EXCIPIENT FREE
This product does not contain wheat, gluten, corn, yeast, soy, egg, dairy products, or artificial colors, sweeteners, or flavors. This product also does not contain lactose, palmitic acid, or magnesium, calcium, or vegetable stearates.

PREGNANCY WARNING
If pregnant, consult your health-care practitioner before using this product.

INTERACTIONS/CONTRAINDICATIONS
There are no known adverse interactions or contraindications at publication date.

OTHER WARNINGS
It is not recommended to remove the Bio-B12 powder from the capsule, as papain can be irritating to the oral mucosa.



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