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Perfusia-SR®

sustained-release L-arginine to support cardiovascular health, nitric oxide production, and optimal blood flow*

when sufficient L-arginine is present:

  • arteries relax, promoting optimal blood flow*
  • as arteries relax, already normal blood pressure can be better maintained*
  • erections occur in the normal course of intimacy*
  • supple, flexible arteries are better able to support good cardiovascular health*

Item Product Size Price
SA525 Perfusia-SR® 120 Vegetarian Capsules $34.80

Product Information

Sustained-release L-arginine supports cardiovascular function, wound healing, and immune function* – and is a biological precursor to nitric oxide*

L-arginine is a semi-essential amino acid involved in multiple areas of human physiology and metabolism. L-arginine significantly affects endocrine function and helps regulate the release of neurotransmitter chemicals, insulin, glucagon (which has the opposite effect of insulin; i.e., it raises blood sugar), and growth hormone.* However, one of L-arginine's most compelling contributions to human physiology is its role as a biological precursor of nitric oxide.* The vascular endothelium (lining of the arteries) creates nitric oxide from L-arginine, resulting primarily in blood vessel relaxation.* This property is critical to maintaining good vascular health, heart health, reproductive health, and protection against oxidative damage.*

Maintaining the natural, healthy functions of the vascular endothelium is dependent upon an adequate supply of L-arginine being available to these cells.* As mentioned above, the conversion of L-arginine to nitric oxide is responsible for these functions by making the endothelial cells more resistant to oxidative damage and adhesion by otherwise harmful substances.* Numerous studies have demonstrated that individuals with sufficient nitric oxide production by endothelial cells have the best opportunity to maintain healthy cardiovascular health.*

In a large, double-blind trial that observed male reproductive health issues, 1.6 g L-arginine daily for six weeks resulted in improvement in reproductive health in those men with low nitric oxide metabolism.*

Like most amino acids, L-arginine functions as a building block of proteins; however, its presence also appears to support wound healing.* Numerous studies show L-arginine supplementation benefits wound healing time and strength of the tissue in and around the wound during the healing phase.*

Without adequate L-arginine (and subsequently, nitric oxide) available to vascular endothelial cells, arteries may not optimally dilate, which can result in less than optimal blood flow to the organs and extremities.*

L-arginine is absorbed and metabolized by the body very quickly, which usually necessitates taking it frequently throughout the day. Sustained-release Perfusia-SR, however, maintains an optimal level of L-arginine over 24 hours with suggested twice-daily use.*

Studies on Perfusia-SR show increased blood flow to the heart muscle and the extremities, maintenance of already normal blood pressure, and improved vascular elasticity.* A recent study demonstrated improvements in blood flow after Perfusia-SR supplementation in individuals with less than optimum heart health.* In another study, Perfusia-SR was given to 29 healthy volunteers for one week and significant support for healthy cardiovascular system was observed.*

Ingredients

Two Capsules Contain:
L-Arginine* 1 g.

Other Ingredients: High and low viscosity hydroxypropyl methylcellulose and MagnesiumCitrateLaurate (Time-Sorb*), Hypromellose (derived from cellulose) capsule, Leucine, Silicon Dioxide.

*L-Arginine complexed with Time-SorbŪ, a time-release matrix.

Suggested Use: Take 2 capsules two times daily or as recommended by your health-care practitioner.

Servings Per Container: 60
Please read the warnings for this product on the warnings tab.

Statements and Warnings

ALLERGY WARNINGS
This product is contraindicated in an individual with a history of hypersensitivity to any of its ingredients.

EXCIPIENT FREE
This product does not contain wheat, gluten, corn, yeast, soy, egg, dairy products, or artificial colors, sweeteners, or flavors. This product also does not contain lactose, palmitic acid, or magnesium, calcium, or vegetable stearates.

PREGNANCY WARNING
If pregnant, consult your health-care practitioner before using this product.

INTERACTIONS/CONTRAINDICATIONS
Individuals with a known herpes infection should not take L-arginine without also taking lysine, as L-arginine alone has been noted to cause herpes eruptions in susceptible individuals. L-arginine supplementation is contraindicated in a patient with hepatocellular carcinoma.

Health-Care Professional Resources

Heart Health Webinar

Alan Miller, ND, presents an explanation of the research behind the use of red yeast rice, methylation promoters, and nitric oxide cofactors for cardiovascular health. This 30-minute webinar explains how L-arginine and specific antioxidants and nutrient and botanical cofactors influence cardiovascular health; how 5-methyltetrahydrofolate (5MTHF - the active form of folate), vitamins B2, B6, B12, and betaine support heart health by reducing homocysteine; and how red yeast rice helps support normal cholesterol levels.

The Importance of L-Arginine in Vascular Endothelial Function and Cardiovascular Health Webinar

Alan L. Miller, ND, Director of Medical Education and Research at Thorne Research, presents information on the essential and versatile amino acid L-arginine and its vital role in cardiovascular health. The presentation offers clinical information on how to optimize cardiovascular health by improving vascular endothelial function with L-arginine and other nutrient cofactors.

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